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Title Computer-assisted adjustment of inspired oxygen concentration improves control of oxygen saturation in newborn infants requiring mechanical ventilation.
Author(s) Yao Sun; Isaac S. Kohane; Ann R. Stark
Source Journal of Pediatrics, Vol. 131, Pages 754-756
Publication Date Nov. 1997
Abstract Open-loop computer control of inspired oxygen concentation was evaluated in 16 newborn infants requiring mechanical ventilation. FiO2 and oxygen saturation were compared for 2-hour periods of computer versus routine manual FiO2 adjustment. During computer-assisted FiO2 adjustment, patients spent more time at the target SaO2 and less time with SaO2 less than 90 percent.

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